236
indexed publications
Evidence · Source-linked
Veterinary oxygen-carrier evidence.
Historical Oxyglobin regulatory evidence and the wider veterinary oxygen-carrier literature are presented together, with the population, endpoint and source boundaries kept explicit.
Original FDA canine field trial
95% treatment success vs 32% control
FDA efficacy population: 20/21 Oxyglobin-treated dogs achieved treatment success versus 9/28 untreated controls; p≤0.001.
Intent-to-treat population: 73% (22/30) vs 29% (10/34); p≤0.001.
Treatment success meant no need for additional oxygen-carrying support for 24 hours. This was not a survival endpoint.
Pivotal multicenter field trial: 64 client-owned anaemic dogs; 30 randomized to Oxyglobin and 34 to untreated control.
Evidence library
236 records. Built to be traceable.
The veterinary index is a source-linked bibliography across 10 species/model groups. It is not a claim that all 236 records are veterinary treatment trials.
235
source-linked citations
225 / 217
PubMed / DOI links
154
author institutions
Indexed groups: canine 25 · feline 6 · equine 4 · porcine 38 · ovine 4 · rodent 39 · avian 18 · exotic/other 15 · human 89 · other/in vitro 21. Records may carry more than one species/model label; group counts must not be added to derive the 236 total.
Scientific publications
Go directly to the full veterinary evidence hub, searchable bibliography, citation catalogue and methodology. No intermediate catalogue page is required to reach the search tool.
Veterinary evidence hubMain source library: 236 records, species/model distribution, institutions, regulatory milestones and evidence routes.Search veterinary publicationsFilter the indexed literature by species, author, institution, journal, year or topic.Full citation catalogueBrowse all 236 retained records with source links, PubMed records, DOI links and affiliations where available.Evidence methodologyHow citation identity, affiliations, species/model labels and evidence limits are handled.
Regulatory records
Oxyglobin is the historical veterinary HBOC precedent. The records below remain product-, species-, jurisdiction- and indication-specific.
FDA / EMA Oxyglobin source libraryOne regulatory route connecting the original US approval, EU authorisation and subsequent source documents.FDA original approval · NADA 141-067Primary FDA Freedom of Information summary. Approval date: 12 January 1998; indication: anaemia in dogs.EMA Oxyglobin EPAR · EMEA/V/C/000045Official European Medicines Agency record for Oxyglobin, haemoglobin glutamer-200 (bovine).
Evidence boundaries: the 95% vs 32% result is the FDA-defined 24-hour treatment-success endpoint in the Oxyglobin efficacy population, not survival. Historical Oxyglobin approvals do not establish BHOC efficacy, BHOC regulatory approval, approval for other species, affiliation or endorsement.